Article

Characterization of the myeloid-specific CD11b promoter

1992-02-15

Abstract excerpt

The CD11b/CD18 heterodimeric surface antigen is expressed exclusively on human monocytes, macrophages, granulocytes, and natural killer cells. During differentiation of myeloid cell lines, CD11b steady state messenger RNA levels increase significantly; we show here that CD11b transcription rates increase commensurately. A 1.7-kb fragment of CD11b 5′ flanking sequence directs expression of a reporter gene specifica...

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Literature Corpus work: d9c9f5d3-8a60-5a2b-b969-eb8998568707
DOI: 10.1182/blood.v79.4.865.bloodjournal794865

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