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Article

CD18 (beta 2 leukocyte integrin) promoter requires PU.1 transcription factor for myeloid activity.

Proceedings of the National Academy of Sciences of the United States of America - 31 Jan 1995

Rosmarin A G, Caprio D, Levy R, Simkevich C

Abstract excerpt

Normal cellular differentiation is linked to tightly regulated gene transcription. However, the DNA elements and trans-acting factors that regulate transcription in myeloid cells are poorly defined. CD18, the beta chain of the leukocyte integrins, is transcriptionally regulated during myeloid differentiation. The CD18 promoter is active after transfection into myeloid cells. We demonstrate that a region of the...

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Identifiers

PMID: 7846055
DOI: 10.1073/pnas.92.3.801
PMCID: PMC42708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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CD18 (beta 2 leukocyte integrin) promoter requires PU.1 transcription factor for myeloid activity.PMID 7846055Read ↗

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