Article
CD18 (beta 2 leukocyte integrin) promoter requires PU.1 transcription factor for myeloid activity.
Proceedings of the National Academy of Sciences of the United States of America - 31 Jan 1995
Rosmarin A G, Caprio D, Levy R, Simkevich C
Abstract excerpt
Normal cellular differentiation is linked to tightly regulated gene transcription. However, the DNA elements and trans-acting factors that regulate transcription in myeloid cells are poorly defined. CD18, the beta chain of the leukocyte integrins, is transcriptionally regulated during myeloid dif...
Topics
- Base Sequence
- Binding Sites
- CD18 Antigens
- Cell Differentiation
- Cell Line
- DNA
- DNA-Binding Proteins
- Molecular Sequence Data
- Monocytes
- Mutation
- Nuclear Proteins
- Promoter Regions, Genetic
- Retroviridae Proteins, Oncogenic
- Tetradecanoylphorbol Acetate
- Transcription Factors
- Transfection