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Article

CCAAT-Enhancer-binding Proteins (C/EBP) Regulate the Tissue Specific Activity of the CD11c Integrin Gene Promoter Through Functional Interactions with Sp1 Proteins

1 Nov 1997

Abstract excerpt

The CD11c/CD18 integrin binds lipopolysaccharide, fibrinogen, and heparin, and mediates leukocyte adhesion, spreading, and migration. CD11c/CD18 is primarily found on myeloid cells and its expression is regulated during myeloid differentiation by transcriptional mechanisms acting on the CD11c gene promoter. We now describe that CCAAT/enhancer-binding proteins (C/EBP) contribute to the basal, tissue-specific and...

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PMID: 9360988
DOI: 10.1074/jbc.272.46.29120

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Related research

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Research trail→

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CCAAT-Enhancer-binding Proteins (C/EBP) Regulate the Tissue Specific Activity of the CD11c Integrin Gene Promoter Through Functional Interactions with Sp1 ProteinsPMID 9360988Read ↗

The human beta 2 integrin CD18 promoter consists of two inverted Ets cis elements.Semantic proximity Read ↗

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The Zinc Finger Transcription Factor Transforming Growth Factor β-Inducible Early Gene-1 Confers Myeloid-specific Activation of the Leukocyte Integrin CD11d PromoterSemantic proximity Read ↗

Induction of C/EBPα activity alters gene expression and differentiation of human CD34+ cellsSemantic proximity Read ↗

CCAAT/enhancer binding protein ɛ is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicingSemantic proximity Read ↗

Identification of a novel DNA regulatory element in the rabbit surfactant protein B (SP-B) promoter that is a target for ATF/CREB and AP-1 transcription factors.Semantic proximity Read ↗

Transcriptional Regulation of the Generic Promoter III of the Rat Prolactin Receptor Gene by C/EBPβ and Sp1Semantic proximity Read ↗

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The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter.Semantic proximity Read ↗

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