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Modulation of Influenza A virus NS1 expression reveals prioritization of host response antagonism at single-cell resolution

9 Oct 2023

Abstract excerpt

Influenza A virus (IAV) is an important human respiratory pathogen that causes significant seasonal epidemics and potential devastating pandemics. As part of its life cycle, IAV encodes the multifunctional protein NS1, that, among many roles, prevents immune detection and limits interferon (IFN) production. As distinct host immune pathways exert different selective pressures against IAV, as replication...

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PMID: 37876781
DOI: 10.3389/fmicb.2023.1267078

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