Article

Detailed single-cell mapping of the transcriptional response to a virus infection driven by copy-back viral genomes

2026-01-06

Abstract excerpt

<h4>Summary</h4> The antiviral response to several clinically significant viruses, including respiratory syncytial virus and parainfluenza virus, is driven by copy-back viral genomes (cbVGs) generated during virus replication. However, the broader impact of cbVGs on the functional states of host cells remains undefined. Here, we developed a single-cell RNA-sequencing and computational framework to map cbVG-driven...

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Literature Corpus work: ba8ac5fc-7c1b-59b7-a4b2-6b5a11743605
DOI: 10.64898/2026.01.06.697933

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