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Article

Microenvironmental Heterogeneity in Brain Malignancies

1 Oct 2019

Abstract excerpt

Brain tumors are among the deadliest malignancies. The brain tumor microenvironment (TME) hosts a unique collection of cells, soluble factors, and extracellular matrix components that regulate disease evolution of both primary and metastatic brain malignancies. It is established that macrophages and other myeloid cells are abundant in the brain TME and strongly correlate with aggressive phenotypes and distinct...

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Identifiers

PMID: 31632393
DOI: 10.3389/fimmu.2019.02294

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