Article

RNA N6-Methyladenosine (m6A) regulates the cell cycle in Diffuse Midline Glioma (DMG) and confers sensitivity to FTO inhibition

2024-11-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Diffuse Midline Gliomas (DMG) are deadly pediatric brain cancers with limited treatment options. These tumors likely arise from oligodendrocyte precursor cells (OPC) that acquire a driver histone mutation, leading to an aberrant epigenome. RNA N6-methyladenosine (m6A) is a vital epi-transcriptomic modification that regulates RNA processes and plays a significant...

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Literature Corpus work: d98ce5e4-ff28-54ac-bd90-b47f6a251d85
DOI: 10.21203/rs.3.rs-5390888/v1

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