Article

Towards enzymatic synthesis of uncharged xeno nucleic acids

2020-01-01

Abstract excerpt

A genetic material is a defining requirement for life. The many practical uses of DNA and RNA have also made these molecules integral tools for human manipulation of biological systems. However, high susceptibility to nuclease degradation and limited chemical diversity constrain their use in therapeutic applications and beyond. Chemically modified analogues of DNA, referred to collectively as xeno nucleic acids (X...

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Literature Corpus work: d986b476-3268-5229-abf0-c79cc8cddd45
DOI: 10.17863/cam.58332

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