Article

hBD-2 Binds SARS-CoV-2 RBD and Blocks Viral Entry: Strategy to Combat COVID-19

2021-02-19

Abstract excerpt

New approaches to complement vaccination are needed to combat the spread of SARS-CoV-2 and stop COVID-19 related deaths and medical complications. Human beta defensin 2 (hBD-2) is a naturally occurring epithelial cell derived host defense peptide that has antiviral properties. Our comprehensive <i>in-silico</i> studies demonstrate that hBD-2 binds the site on the CoV-2-RBD that docks with the ACE2 receptor. Bioph...

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Literature Corpus work: d9845ac9-b38f-5ef9-bc80-43c1ccd6e44b
DOI: 10.2139/ssrn.3789259

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