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A potent neutralizing nanobody against SARS-CoV-2 with inhaled delivery potential

2020-08-10

Abstract excerpt

The outbreak of COVID-19 has emerged as a global pandemic. The unprecedented scale and severity call for rapid development of effective prophylactics or therapeutics. We here reported Nanobody (Nb) phage display libraries derived from four camels immunized with the SARS-CoV-2 spike receptor-binding domain (RBD), from which 381 Nbs were identified to recognize SARS-CoV-2-RBD. Furthermore, seven Nbs were shown to bl...

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Identifiers and source

Literature Corpus work
048f92ae-5160-5296-ba8a-dd885e64b45b
DOI
10.1101/2020.08.09.242867
Open publication

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A potent neutralizing nanobody against SARS-CoV-2 with inhaled delivery potentialDOI 10.1101/2020.08.09.242867
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