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A novel intranasal administration adenoviral vector-based platform for rapid COVID-19 vaccine development

2022-02-22

Abstract excerpt

The coronavirus SARS-CoV-2 has a severe impact on global public health, and the emerging variants threaten the efficacy of the circulating vaccines. Here, we report that a single vaccination with a non-replicating chimpanzee adenovirus-based vaccine against the SARS-CoV-2 Delta variant (JS1-delta) elicits potent humoral, cellular and mucosal immunity in mice. Additionally, a single intranasal administration of JS1...

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Identifiers and source

Literature Corpus work
d96e82a3-96f7-5d47-8d8e-ea8f6164cbdb
DOI
10.1101/2022.02.21.481247
Open publication

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A novel intranasal administration adenoviral vector-based platform for rapid COVID-19 vaccine developmentDOI 10.1101/2022.02.21.481247
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