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Single-dose respiratory mucosal delivery of next-generation viral-vectored COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2

2021-07-19

Abstract excerpt

<h4>Summary</h4> The emerging SARS-CoV-2 variants of concern (VOC) increasingly threaten the effectiveness of current first-generation COVID-19 vaccines that are administered intramuscularly and are designed to only target the spike protein. There is thus a pressing need to develop next-generation vaccine strategies to provide more broad and long-lasting protection. By using adenoviral vectors (Ad) of human and c...

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Literature Corpus work
7b7ca4a6-d79b-5739-acd5-2353a4a673b3
DOI
10.1101/2021.07.16.452721
Open publication

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Single-dose respiratory mucosal delivery of next-generation viral-vectored COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2DOI 10.1101/2021.07.16.452721
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