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Single-dose immunization with a chimpanzee adenovirus-based vaccine induces sustained and protective immunity against SARS-CoV-2 infection

2021-02-23

Abstract excerpt

<title>Abstract</title> <p>The development of an effective vaccine against SARS-CoV-2, the causative agent of pandemic coronavirus disease-2019 (COVID-19), is a global priority. Here, we present three chimpanzee adenovirus vaccines that express either the full-length spike (ChAdTS-S), or receptor-binding domain (RBD) with two different signal sequences (ChAdTS-RBD and ChAdTS-RBDs). Single-dose intranasal or intra...

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Literature Corpus work
689ba9d9-2078-546e-bf6f-8907b719e1e8
DOI
10.21203/rs.3.rs-155550/v1
Open publication

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Single-dose immunization with a chimpanzee adenovirus-based vaccine induces sustained and protective immunity against SARS-CoV-2 infectionDOI 10.21203/rs.3.rs-155550/v1
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