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Article

A quadrivalent norovirus vaccine based on a chimpanzee adenovirus vector induces potent immunity in mice.

Virologica Sinica - 1 Aug 2024

Jiang Yihua, Sun Lingjin, Qiao Nan, Wang Xiang, Zhu Caihong, Xing Man, Liu Hui, Zhou Ping, Zhou Dongming

Abstract excerpt

Norovirus (NoV) infection is a major cause of gastroenteritis worldwide. The virus poses great challenges in developing vaccines with broad immune protection due to its genetic and antigenic diversity. To date, there are no approved NoV vaccines for clinical use. Here, we aimed to develop a broad-acting quadrivalent NoV vaccine based on a chimpanzee adenovirus vector, AdC68, carrying the major capsid protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38997087
DOI: 10.1016/j.virs.2024.07.002
PMCID: PMC11401472

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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