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Durable immunity to SARS-CoV-2 in both lower and upper airways achieved with a gorilla adenovirus (GRAd) S-2P vaccine in non-human primates

2023-11-22

Abstract excerpt

<h4>Summary</h4> SARS-CoV-2 continues to pose a global threat, and current vaccines, while effective against severe illness, fall short in preventing transmission. To address this challenge, there’s a need for vaccines that induce mucosal immunity and can rapidly control the virus. In this study, we demonstrate that a single immunization with a novel gorilla adenovirus-based vaccine (GRAd) carrying the pre-fusion...

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Identifiers and source

Literature Corpus work
20081ce3-2917-56e5-8371-0bb1a82810e3
DOI
10.1101/2023.11.22.567930
Open publication

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