Article

A quantitative and site-specific atlas of the in vivo citrullinome reveals widespread existence of citrullination

2022-12-22

Abstract excerpt

Citrullination is the conversion of peptidyl-arginine into the non-coded amino acid citrulline. Despite its importance in physiology and disease, global identification of citrullinated proteins and precise modification sites has remained challenging. Here, we employed quantitative mass spectrometry-based proteomics to generate a comprehensive atlas of citrullination sites in a physiologically relevant cell type. C...

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Literature Corpus work: d91cf0af-8810-512d-b622-9f5054a9b8fb
DOI: 10.1101/2022.12.22.521572

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