Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PAD4: pathophysiology, current therapeutics and future perspective in rheumatoid arthritis

16 Feb 2017

Abstract excerpt

INTRODUCTION: Peptidyl arginine deiminase 4 (PAD4) is an enzyme that plays an important role in gene expression, turning out genetic code into functional products in the body. It is involved in a key post translational modification, which involves the conversion of arginine to citrulline. It regulates various processes such as apoptosis, innate immunity and pluripotency, while its dysregulation has a great impact...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Peptidase Inhibition and Analysis
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28281906
DOI: 10.1080/14728222.2017.1294160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PAD4: pathophysiology, current therapeutics and future perspective in rheumatoid arthritisPMID 28281906Read ↗

Peptidyl Arginine Deiminases in Chronic Diseases: A Focus on Rheumatoid Arthritis and Interstitial Lung DiseaseSemantic proximity Read ↗

PAD enzymes in rheumatoid arthritis: pathogenic effectors and autoimmune targets.Semantic proximity Read ↗

PAD, a growing family of citrullinating enzymes: genes, features and involvement in diseaseSemantic proximity Read ↗

Peptidylarginine deiminase type 4: identification of a rheumatoid arthritis-susceptible gene.Semantic proximity Read ↗

Peptidylarginine deiminase 4 and citrullination in health and disease.Semantic proximity Read ↗

Alleviation of arthritis through prevention of neutrophil extracellular traps by an orally available inhibitor of protein arginine deiminase 4Semantic proximity Read ↗

A common missense variant rs874881 of PADI4 gene and rheumatoid arthritis: Genetic association study and in-silico analysis.Semantic proximity Read ↗

From genetics to functional insights into rheumatoid arthritis.Semantic proximity Read ↗

PADI2 is significantly associated with rheumatoid arthritis.Semantic proximity Read ↗

Molecular Factors in PAD2 (PADI2) and PAD4 (PADI4) Are Associated with Interstitial Lung Disease Susceptibility in Rheumatoid Arthritis Patients.Semantic proximity Read ↗

Role of citrullination modification catalyzed by peptidylarginine deiminase 4 in gene transcriptional regulationSemantic proximity Read ↗

Citrullination by peptidylarginine deiminase in rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.