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Article

An Overview of the Intrinsic Role of Citrullination in Autoimmune Disorders.

Journal of immunology research - 1 Jan 2019

Alghamdi Mohammed, Alasmari Doaa, Assiri Amjad, Mattar Ehab, Aljaddawi Abdullah A, Alattas Sana G, Redwan Elrashdy M

Abstract excerpt

A protein undergoes many types of posttranslation modification. Citrullination is one of these modifications, where an arginine amino acid is converted to a citrulline amino acid. This process depends on catalytic enzymes such as peptidylarginine deiminase enzymes (PADs). This modification leads to a charge shift, which affects the protein structure, protein-protein interactions, and hydrogen bond formation, and...

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Source

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Identifiers

PMID: 31886309
DOI: 10.1155/2019/7592851
PMCID: PMC6899306

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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