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Insights into the study and origin of the citrullinome in rheumatoid arthritis

25 Dec 2019

Abstract excerpt

The presence of autoantibodies and autoreactive T cells to citrullinated proteins and citrullinating enzymes in patients with rheumatoid arthritis (RA), together with the accumulation of citrullinated proteins in rheumatoid joints, provides substantial evidence that dysregulated citrullination is a hallmark feature of RA. However, understanding mechanisms that dysregulate citrullination in RA has important...

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PMID: 31876028
DOI: 10.1111/imr.12834

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