Article

Genome Near-Haploidization in CDC73-Wildtype Parathyroid Tumors

2025-10-20

Abstract excerpt

<title>Abstract</title> <p> Recurring parathyroid carcinoma (PC) is foremost associated with germline or somatic <italic>CDC73</italic> mutations. We reported three PCs without <italic>CDC73</italic> mutations, with massive chromosomal losses, genome near-haploidization with or without endoreduplication/genome doubling. These are characteristic features seen in rare tumor types like oncocytic thyroid carcino...

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Literature Corpus work: d90ef0de-f747-5fb0-b1ba-cbbe703f393b
DOI: 10.21203/rs.3.rs-7834367/v1

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