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Genetics and Epigenetics of Parathyroid Carcinoma

24 Feb 2022

Abstract excerpt

Parathyroid carcinoma (PC) is an extremely rare malignancy, accounting less than 1% of all parathyroid neoplasms, and an uncommon cause of primary hyperparathyroidism (PHPT), characterized by an excessive secretion of parathyroid hormone (PTH) and severe hypercalcemia. As opposed to parathyroid hyperplasia and adenomas, PC is associated with a poor prognosis, due to a commonly unmanageable hypercalcemia, which...

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PMID: 35282432
DOI: 10.3389/fendo.2022.834362

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