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Article

Genome-wide and locus specific alterations in CDC73/HRPT2-mutated parathyroid tumors.

PloS one - 1 Jan 2012

Sulaiman Luqman, Haglund Felix, Hashemi Jamileh, Obara Takao, Nordenström Jörgen, Larsson Catharina, Juhlin C Christofer

Abstract excerpt

Mutations in the hyperparathyroidism type 2 (HRPT2/CDC73) gene and alterations in the parafibromin protein have been established in the majority of parathyroid carcinomas and in subsets of parathyroid adenomas. While it is known that CDC73-mutated parathyroid tumors display specific gene expression changes compared to CDC73 wild-type cases, the molecular cytogenetic profile in CDC73-mutated cases compared to...

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Source

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Identifiers

PMID: 23029479
DOI: 10.1371/journal.pone.0046325
PMCID: PMC3460869

Genes

CDC73

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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