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Real-time measurements of ATP dynamics via ATeams in <i>Plasmodium falciparum</i> reveal drug-class-specific response patterns

2023-12-21

Abstract excerpt

Malaria tropica , caused by the parasite Plasmodium falciparum ( P. falciparum ) remains one of the greatest public health burdens for humankind. Due to its pivotal role in parasite survival, the energy metabolism of P. falciparum is an interesting target for drug design. To this end, analysis of the central metabolite ATP is of great interest. So far, only cell disruptive or intensiometric ATP assays have been...

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Literature Corpus work
d90151e5-2f05-57de-a27f-9a6e92304df2
DOI
10.1101/2023.12.20.572598
Open publication

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Real-time measurements of ATP dynamics via ATeams in <i>Plasmodium falciparum</i> reveal drug-class-specific response patternsDOI 10.1101/2023.12.20.572598
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