Article

N-Glycans Modulate HIV-1 Env Conformational Plasticity

2025-03-26

Abstract excerpt

Human immunodeficiency virus-1 (HIV-1) remains a global health crisis, with over 39 million people living with the virus and no effective vaccine available. Central to HIV infection and immune evasion is the envelope glycoprotein (Env), a heavily glycosylated class I fusion protein that mediates viral entry and is the sole immunogenic target. Despite the recent advancements provided by imaging techniques, the char...

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Literature Corpus work: b68c67aa-9561-5a49-89b3-7340e12a74be
DOI: 10.1101/2025.03.26.645577

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