Article

Conservation of Long G4-rich (LG4) genomic enhancer regulations

2026-03-13

Abstract excerpt

Long G4-rich regions (LG4s) are defined as DNA sequences containing a high density of guanine triplets capable of forming non-B DNA structures called G-quadruplexes (G4s). These regions frequently overlap with enhancers, which are regulatory DNA elements that modulate gene expression by interacting with DNA regions that dictate where transcription is initiated known as promoters. While LG4s have now been well-char...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d89b20de-8be5-5896-ab88-c0bb0506ac3e
DOI: 10.64898/2026.03.11.711068

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Conservation of Long G4-rich (LG4) genomic enhancer regulationsDOI 10.64898/2026.03.11.711068Read

Novel Roles of G-quadruplexes on Enhancers in human chromatinSemantic proximity Read

The Encyclopedia of DNA ElementsSemantic proximity Read

Long G4-rich enhancer physically interacts with EXOC3 promoter via a G4:G4 DNA-based mechanismSemantic proximity Read

Enhancers: five essential questions.Semantic proximity Read

G-quadruplexes as pivotal components of <i>cis</i> -regulatory elements in the human genomeSemantic proximity Read

Genetic features and genomic targets of human KRAB-Zinc Finger ProteinsSemantic proximity Read

An integrated encyclopedia of DNA elements in the human genome.Semantic proximity Read

Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop 'G4 Kissing' interaction.Semantic proximity Read

From remote enhancers to gene regulation: charting the genome's regulatory landscapes.Semantic proximity Read

Short DNA sequence patterns accurately identify broadly active human enhancersSemantic proximity Read

Enhancer-gene maps in the human and zebrafish genomes using evolutionary linkage conservationSemantic proximity Read

Variation and selection at predicted G-quadruplexes across the human pangenomeSemantic proximity Read