Article

Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq): A versatile and ultra-sensitive UMI-based NGS library preparation technology, for use with cfDNA and cfRNA

2020-07-12

Abstract excerpt

Liquid biopsy testing utilising Next Generation Sequencing (NGS) is rapidly moving towards clinical adoption for personalised oncology. However, before NGS can fulfil its potential any novel testing approach must identify ways of reducing errors, allowing for separating true low-frequency mutations from procedural artefacts, and be designed to improve upon current technologies while also avoiding their limitations...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d82af63a-a729-5dee-8dcd-a044b111976e
DOI: 10.1101/2020.07.10.152405

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq): A versatile and ultra-sensitive UMI-based NGS library preparation technology, for use with cfDNA and cfRNADOI 10.1101/2020.07.10.152405Read

Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA.Semantic proximity Read

Use of FFPE-Derived DNA in Next Generation Sequencing: DNA extraction methodsSemantic proximity Read

Use of FFPE-derived DNA in next generation sequencing: DNA extraction methodsSemantic proximity Read

Tissue-based next generation sequencing: application in a universal healthcare system.Semantic proximity Read

TargetPlex FFPE-Direct DNA Library Preparation Kit for SiRe NGS panel: an international performance evaluation study.Semantic proximity Read

Quality metrics for enhanced performance of an NGS panel using single-vial amplification technology.Semantic proximity Read

Duplex Proximity Sequencing (Pro-Seq): A method to improve DNA sequencing accuracy without the cost of molecular barcoding redundancySemantic proximity Read

A straightforward assay to evaluate DNA integrity and optimize next-generation sequencing for clinical diagnosis in oncology.Semantic proximity Read

Quantifying sequencing error and effective sequencing depth of liquid biopsy NGS with UMI error correction.Semantic proximity Read

Validation of the NovaSeq6000 Platform and automated library preparation for CE-IVD equivalenceSemantic proximity Read

Rapid and highly-specific generation of targeted DNA sequencing libraries enabled by linking capture probes with universal primersSemantic proximity Read

Idylla assay and next generation sequencing: an integrated EGFR mutational testing algorithm.Semantic proximity Read