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Article

Use of FFPE-Derived DNA in Next Generation Sequencing: DNA extraction methods

2019-01-15

Abstract excerpt

Archival tissues represent a rich resource for clinical genomic studies, particularly when coupled with comprehensive medical records. Use of these in NGS is a priority. Nine formalin-fixed paraffin-embedded (FFPE) DNA extraction methods were evaluated using twelve FFPE samples of varying tissue types. Quality assessment included total yield, percent ds DNA, fragment analysis and multiplex PCR. After assessment, t...

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Identifiers and source

Literature Corpus work
7e69e25a-1b7c-5c6d-8f82-979de8a7d4d8
DOI
10.1101/521534
Open publication

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Use of FFPE-Derived DNA in Next Generation Sequencing: DNA extraction methodsDOI 10.1101/521534
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