Article
Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA.
Scientific reports - 4 Feb 2021
Dunwell Thomas L, Dailey Simon C, Ottestad Anine L, Yu Jihang, Becker Philipp W, Scaife Sarah, Richman Susan D, Wood Henry M, Slaney Hayley, Bottomley Daniel, Yang Xiangsheng, Xiao Hui, Wahl Sissel G F, Grønberg Bjørn H, Dai Hongyan, Fu Guoliang
Abstract excerpt
Liquid biopsy testing utilising Next Generation Sequencing (NGS) is rapidly moving towards clinical adoption for personalised oncology. However, before NGS can fulfil its potential any novel testing approach must identify ways of reducing errors, allowing separation of true low-frequency mutations from procedural artefacts, and be designed to improve upon current technologies. Popular NGS technologies typically...
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