Article
Idylla assay and next generation sequencing: an integrated EGFR mutational testing algorithm.
Journal of clinical pathology - 1 Aug 2018
De Luca Caterina, Rappa Alessandra G, Gragnano Gianluca, Malapelle Umberto, Troncone Giancarlo, Barberis Massimo
Abstract excerpt
AIMS: Any reference laboratory testing non-small cell lung cancer samples for predictive biomarkers needs to develop and validate a wide range of different molecular techniques, each with a specific time requirement and application. Updated international guidelines suggest that next generation sequencing (NGS) to be the initial procedure. However, in a non-negligible subset of cases, library generation may fail...
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