Article

Ku limits aberrant mRNA splicing promoted by intronic antisense Alu elements

2025-11-20

Abstract excerpt

<h4>Summary</h4> Alu elements are short repeats that occupy approximately 10% of the human genome 1,2 . Saturation of primate genomes with Alu sequences occurred at the prosimian/new-world monkey evolutionary juncture. Alu elements have clearly driven unique aspects of higher primate evolution, but their presence can be detrimental to genomic stability 3 . The expansion of Alu sequences in the genomes of higher...

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Literature Corpus work: d80fd294-95a5-584e-a9cf-922d2cb6505a
DOI: 10.1101/2025.11.20.689478

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