Article

Inverted Alu repeats in loop-out exon skipping across hominoid evolution

2025-03-11

Abstract excerpt

<h4>Background</h4> Changes in RNA splicing over the course of evolution have profoundly diversified the functional landscape of the human genome. While DNA sequences proximal to intron-exon junctions are known to be critical for RNA splicing, the impact of distal intronic sequences remains underexplored. Emerging evidence suggests that inverted pairs of intronic Alu elements can promote exon skipping by forming...

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Literature Corpus work: 60bb8b11-8a54-56d4-9879-51b74c211449
DOI: 10.1101/2025.03.07.642063

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