Article

Extracellular matrix context shapes morphogenesis and lactation-associated states in human milk-derived mammary organoids

2026-08-24

Abstract excerpt

The mammary gland relies on reciprocal interactions between epithelial cells and their surrounding extracellular matrix (ECM) to form and maintain milk-producing tissue structures. Yet these processes remain difficult to study in human model systems. Mammary epithelial cells (MECs) can be isolated noninvasively from breast milk, but whether they generate three-dimensional organoids and respond to matrix cues has b...

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Literature Corpus work: d7f39c84-121d-5713-bd90-b76e42ccd82d
DOI: 10.64898/2026.08.23.746503

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