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Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk

28 Jan 2022

Abstract excerpt

Under normal conditions, the most significant expansion and differentiation of the adult mammary gland occurs in response to systemic reproductive hormones during pregnancy and lactation to enable milk synthesis and secretion to sustain the offspring. However, human mammary tissue remodelling that takes place during pregnancy and lactation remains poorly understood due to the challenge of acquiring samples. We...

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PMID: 35091553
DOI: 10.1038/s41467-021-27895-0

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