Article
The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures.
BMC cancer - 7 Jun 2010
Krause Silva, Maffini Maricel V, Soto Ana M, Sonnenschein Carlos
Abstract excerpt
BACKGROUND: Stromal-epithelial interactions mediate breast development, and the initiation and progression of breast cancer. In the present study, we developed 3-dimensional (3D) in vitro models to study breast cancer tissue organization and the role of the microenvironment in phenotypic determin...
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