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Article

Identification of the Collagen Types Essential for Mammalian Breast Acinar Structures

18 Dec 2022

Abstract excerpt

Modeling human breast tissue architecture is essential to study the pathophysiological conditions of the breast. We report that normal mammary epithelial cells grown in human breast extracellular matrix (ECM) hydrogel formed acini structurally similar to those of human and pig mammary tissues. Type I, II, III and V collagens were commonly identified in human, pig, and mouse breast ECM. Mammary epithelial cells...

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PMID: 36547361
DOI: 10.3390/gels8120837

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