Article

fluxTrAM: Integration of tracer-based metabolomics data into atomically resolved genome-scale metabolic networks for metabolic flux analysis

2024-12-02

Abstract excerpt

Quantitative inference of intracellular reaction rates is essential for characterising metabolic phenotypes. The classical experimental method for measuring metabolic fluxes makes use of stable-isotope tracing of metabolites through the metabolic network, followed by mass spectrometry analysis. The most common 13 C-based metabolic flux analysis requires multidisciplinary knowledge in analytical chemistry, cell bi...

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Literature Corpus work: d7cde9d1-4d8f-51c9-9ced-dbf44b17f4bb
DOI: 10.1101/2024.11.26.625485

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