Article
A network-based approach for predicting key enzymes explaining metabolite abundance alterations in a disease phenotype.
BMC systems biology - 19 Jul 2013
Pey Jon, Tobalina Luis, de Cisneros Joaquín Prada J, Planes Francisco J
Abstract excerpt
BACKGROUND: The study of metabolism has attracted much attention during the last years due to its relevance in various diseases. The advance in metabolomics platforms allows us to detect an increasing number of metabolites in abnormal high/low concentration in a disease phenotype. Finding a mechanistic interpretation for these alterations is important to understand pathophysiological processes, however it is not...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.