Article

Comparison of different computational frameworks for metabolic modeling from single-cell transcriptomics data in glioblastoma

2026-03-03

Abstract excerpt

Metabolic reprogramming is a hallmark of glioblastoma, yet how distinct malignant and tumor microenvironment cell populations contribute to this metabolic heterogeneity remains poorly defined. Since direct single-cell metabolomics remains technically limited, transcriptomics-based computational inference offers a powerful alternative. Here we apply and systematically compare three complementary computational metho...

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Literature Corpus work: 96d70463-12f1-55b2-a767-3d5a378820b4
DOI: 10.64898/2026.02.28.706749

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