Article

Changes in neuronal genes in prenatally alcohol-exposed placentas associate with neuropsychological traits at the age of six

2026-01-22

Abstract excerpt

<h4>ABSTRACT</h4> Prenatal alcohol exposure (PAE) disrupts embryonic development and gives rise to a variable fetal alcohol spectrum disorder (FASD) phenotype characterized by neurodevelopmental and dysmorphological defects. We investigated the effects of PAE on placental gene regulation by performing genome-wide DNA methylation (DNAm) microarray and gene expression (3’mRNA sequencing) analyses in 87 PAE, 77 unex...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d7b3b792-72e0-5dc2-9cbd-832dd061b65d
DOI: 10.64898/2026.01.21.26344516

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Changes in neuronal genes in prenatally alcohol-exposed placentas associate with neuropsychological traits at the age of sixDOI 10.64898/2026.01.21.26344516Read

Dysmorphological and neuropsychological phenotypes of prenatally alcohol-exposed six-year-old childrenSemantic proximity Read

Dysmorphological and Neuropsychological Phenotypes of Prenatally Alcohol-Exposed 6-Year-Old Children: A Prospective Longitudinal Birth Cohort Study.Semantic proximity Read

In utero exposure to maternal smoking is associated with DNA methylation alterations and reduced neuronal content in the developing fetal brainSemantic proximity Read

Epigenetic Mechanisms in Developmental Alcohol-Induced Neurobehavioral DeficitsSemantic proximity Read

Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disordersSemantic proximity Read

Combined transcriptome analysis of fetal human and mouse cerebral cortex exposed to alcoholSemantic proximity Read

Overview of the Genetic Basis and Epigenetic Mechanisms that Contribute to FASD PathobiologySemantic proximity Read

Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders.Semantic proximity Read

Associative DNA Methylation Changes in Children with Prenatal Alcohol ExposureSemantic proximity Read

Epigenetic Impacts of Early Life Stress in Fetal Alcohol Spectrum Disorders Shape the Neurodevelopmental ContinuumSemantic proximity Read

Genome-wide DNA methylation analysis of hippocampal tissue in a murine model of Attention Deficit-Hyperactivity DisorderSemantic proximity Read

DNA methylation signature of human fetal alcohol spectrum disorderSemantic proximity Read