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Associative DNA Methylation Changes in Children with Prenatal Alcohol Exposure

16 Jul 2015

Abstract excerpt

AIM: Prenatal alcohol exposure (PAE) can cause fetal alcohol spectrum disorders (FASD). Previously, we assessed PAE in brain tissue from mouse models, however whether these changes are present in humans remains unknown. MATERIALS & METHODS: In this report, we show some identical changes in DNA methylation in the buccal swabs of six children with FASD using the 450K array. RESULTS: The changes occur in genes...

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PMID: 26178076
DOI: 10.2217/epi.15.60

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