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DNA methylation signature of human fetal alcohol spectrum disorder

29 Jun 2016

Abstract excerpt

BACKGROUND: Prenatal alcohol exposure is the leading preventable cause of behavioral and cognitive deficits, which may affect between 2 and 5 % of children in North America. While the underlying mechanisms of alcohol's effects on development remain relatively unknown, emerging evidence implicates epigenetic mechanisms in mediating the range of symptoms observed in children with fetal alcohol spectrum disorder...

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PMID: 27358653
DOI: 10.1186/s13072-016-0074-4

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