Article
Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.
Human genetics - 1 Mar 2017
Leslie Elizabeth J, Carlson Jenna C, Shaffer John R, Butali Azeez, Buxó Carmen J, Castilla Eduardo E, Christensen Kaare, Deleyiannis Fred W B, Leigh Field L, Hecht Jacqueline T, Moreno Lina, Orioli Ieda M, Padilla Carmencita, Vieira Alexandre R, Wehby George L, Feingold Eleanor, Weinberg Seth M, Murray Jeffrey C, Beaty Terri H, Marazita Mary L
Abstract excerpt
Nonsyndromic orofacial clefts (OFCs) are a heterogeneous group of common craniofacial birth defects with complex etiologies that include genetic and environmental risk factors. OFCs are commonly categorized as cleft lip with or without cleft palate (CL/P) and cleft palate alone (CP), which have historically been analyzed as distinct entities. Genes for both CL/P and CP have been identified via multiple...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.