Article

A Single Chimeric Spike Antigen Induces Pan-Sarbecovirus Immunity

2024-11-07

Abstract excerpt

Next-generation vaccines are required to address the evolving nature of SARS-CoV-2 and to protect against emerging pandemic threats from other coronaviruses. These vaccines should aim to elicit broad-protection, provide long-lasting immunity and facilitate equitable access for all populations. In this study, a panel of chimeric, full-length spike antigens were developed that incorporate mutations from previous, ci...

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Literature Corpus work: d76a8bf6-3508-5f1a-a53c-5087875f3413
DOI: 10.1101/2024.11.06.622391

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