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A Multi-Antigen Broad-Spectrum Coronavirus Vaccine Induces Potent and Durable Cross- Protection Against Infection and Disease Caused by Multiple SARS-CoV-2 Variants

2025-08-20

Abstract excerpt

<title>Abstract</title> <p>The first generation of Spike-based COVID-19 vaccines has reduced the risk of hospitalization, serious illness, and death caused by SARS-CoV-2 infections. However, waning immunity induced by these vaccines has failed to prevent immune escape, resulting in the emergence of multiple variants of concern (VOCs) and the prolongation of the COVID-19 pandemic. We hypothesize that a next-genera...

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Literature Corpus work
ee167266-4e51-54f9-97ee-28b74aeeff52
DOI
10.21203/rs.3.rs-7208748/v1
Open publication

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