Article

An ancestry-matched Mendelian randomisation analysis of kidney function and heart failure subtypes in African ancestry populations

2026-07-17

Abstract excerpt

Chronic kidney disease and heart failure disproportionately burden populations of African ancestry, yet Mendelian randomisation (MR) studies of the causal relationship between kidney function and heart failure subtypes have been conducted exclusively in European ancestry populations. We performed a forward two-sample MR analysis to evaluate the causal effect of genetically predicted estimated glomerular filtration...

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Literature Corpus work: d721a255-a97d-55b0-898a-8b86f21d52a5
DOI: 10.64898/2026.07.15.26358145

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