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Article

The causal effects of lipid traits on kidney function in Africans: bidirectional and multivariable Mendelian-randomization study.

EBioMedicine - 1 Apr 2023

Kintu Christopher, Soremekun Opeyemi, Kamiza Abram B, Kalungi Allan, Mayanja Richard, Kalyesubula Robert, Bagaya S Bernard, Jjingo Daudi, Fabian June, Gill Dipender, Nyirenda Moffat, Nitsch Dorothea, Chikowore Tinashe, Fatumo Segun

Abstract excerpt

BACKGROUND: Observational studies have investigated the effect of serum lipids on kidney function, but these findings are limited by confounding, reverse causation and have reported conflicting results. Mendelian randomization (MR) studies address this confounding problem. However, they have been conducted mostly in European ancestry individuals. We, therefore, set out to investigate the effect of lipid traits on...

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Identifiers

PMID: 37001235
DOI: 10.1016/j.ebiom.2023.104537
PMCID: PMC10070509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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