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Atrial fibrillation and kidney function: a bidirectional Mendelian randomization study.

European heart journal - 31 Jul 2021

Park Sehoon, Lee Soojin, Kim Yaerim, Lee Yeonhee, Kang Min Woo, Kim Kwangsoo, Kim Yong Chul, Han Seung Seok, Lee Hajeong, Lee Jung Pyo, Joo Kwon Wook, Lim Chun Soo, Kim Yon Su, Kim Dong Ki

Abstract excerpt

AIMS: The aim of this study was to investigate the causal effects between atrial fibrillation (AF) and kidney function. METHODS AND RESULTS: We performed a bidirectional summary-level Mendelian randomization (MR) analysis implementing the results from a large-scale genome-wide association study for estimated glomerular filtration rate (eGFR) by the CKDGen (N = 765 348) and AF (N = 588 190) to identify genetic...

Topics

Atrial Fibrillation
Genome-Wide Association Study
Humans
Kidney
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34023889
DOI: 10.1093/eurheartj/ehab291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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