Article

Deep and Quantitative Proteomic Profiling of Low Volume Mouse Serum Across the Lifespan

2025-07-31

Abstract excerpt

<title>Abstract</title> <p>Assessing and validating circulating biomarkers is essential for the development of pre-clinical biomarkers that predict biological aging and aging-phenotypes in mice. However, comprehensive proteomics of serum, especially in longitudinal mouse studies, are limited by low volumes of samples. In this study, we develop a workflow for comprehensive and quantitative proteomic analysis of lo...

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Literature Corpus work: d6f68f0d-6a68-5013-b363-be3bdc62c556
DOI: 10.21203/rs.3.rs-7179817/v1

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