Article

Deep and Quantitative Proteomic Profiling of Low Volume Mouse Serum Across the Lifespan

2025-06-27

Abstract excerpt

<h4>ABSTRACT</h4> Assessing and validating circulating biomarkers is essential for the development of pre-clinical biomarkers that predict biological aging and aging-phenotypes in mice. However, comprehensive proteomics of serum, especially in longitudinal mouse studies, are limited by low volumes of samples. In this study, we develop a workflow for comprehensive and quantitative proteomic analysis of low volume...

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Identifiers and source

Literature Corpus work: 92ee78ab-4744-5315-b05e-0349ef5dcf37
DOI: 10.1101/2025.06.24.661372

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