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Article

Distinct and diverse chromatin-proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions

2021-09-12

Abstract excerpt

<h4>SUMMARY</h4> Temporal molecular changes in ageing mammalian organs are of relevance to disease etiology because many age-related diseases are linked to changes in the transcriptional and epigenetic machinery that regulate gene expression. We performed quantitative proteome analysis of chromatin-enriched protein extracts to investigate the dynamics of the chromatin-proteomes of the mouse brain, heart, lung, ki...

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Literature Corpus work
1d674f51-77fa-5047-886b-65f508e4cee9
DOI
10.1101/2021.09.09.459706
Open publication

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Distinct and diverse chromatin-proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functionsDOI 10.1101/2021.09.09.459706
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